What is a Nuclear Exercise Treadmill Test?
Nuclear Exercise Treadmill Test ( nuclear stress test) lets doctors see pictures of your heart while you are resting and shortly after you have exercised. The test can give information about the size of the heart's chambers, how well the heart is pumping blood, and whether the heart has any damaged or dead muscle. Nuclear stress tests can also give doctors information about your arteries and whether they might be narrowed or blocked because of coronary artery disease.
This test is similar to the standard treadmill exercise test. Your
doctor will give you a small amount of a radioactive substance
(sestamibi or thallium) just before the end of the exercise part of the
test. This radioactive substance is not harmful to your body or your
organs. The results of the nuclear stress test can show doctors if the
heart is not working properly while you are resting, exercising, or
both. If the test shows that blood flow is normal while you are resting
but not normal while you are exercising, then doctors know that your
blood flow to your heart is not adequate during times of stress. The
heart normally pumps more blood during times of physical exertion. If
the test results are not normal during both parts of the test (rest and
exercise), part of your heart is permanently deprived of blood or is
scarred. If doctors cannot see the radioactive substance in one part of
your heart, it may mean that a section of heart muscle has died, either
because of a previous heart attack or because the coronary arteries
supplying blood to that area of the heart are blocked.
Pharmacological testing with Dobutamine or Adenosine is performed in
patients who are physically too weak or debilitated to walk on the
treadmill.

How the test is performed:
Just like the exercise stress test, you will have small metal disks
called electrodes placed on your chest and back. The electrodes are
attached to leads, which are attached to an electrocardiogram machine.
Doctors will then have you walk on a treadmill.
After your doctors have the information they need from the exercise
part of the test, you will step off of the treadmill and go into
another room. You will be given an injection of a radioactive
substance, and you will be asked to lie on an examination table, which
has a gamma-ray camera above it. The camera is used to take pictures of
your heart. The camera can pick up traces of the radioactive substance
in your body and then send a picture to a television monitor.
After this part of the test is over, you can leave the testing area for
3 or 4 hours. Doctors will ask you not to exercise or drink or eat
anything with caffeine, such as coffee, tea, sodas, or chocolate. When
you return, doctors will give you another injection of the radioactive
substance. You will be asked to lie down on the examination table, and
the gamma-ray camera will take pictures of your heart while you are
resting. This will give your doctor an idea of how your heart works
during both exercise and rest.
After the test is over, you may eat, drink, and go back to your normal activities right away.
How to prepare for the test:
Patients are generally asked not to eat or drink anything for four to
six hours before the test, and to wear comfortable clothes/shoes for
exercising.
How the test will feel:
Electrodes (conductive patches) will be placed on your chest, arms, and
legs to record the heart's activity. The preparation of the electrode
sites on your chest may produce a mild burning or stinging sensation.
The blood pressure cuff on your arm will be inflated every few minutes,
producing a squeezing sensation that may feel tight. Baseline
measurements of heart rate and blood pressure will be taken before
exercise starts.
You will start walking on a treadmill or pedaling a stationary bicycle.
The pace of the treadmill will be increased. Aside from some
possible discomfort as the radionuclide substance is injected
(twice),this is a painless test.