What is a Nuclear Pharmacologic Testing?

A Nuclear Pharmacologic test with Dobutamine or Adenosine is performed in patients who are physically too weak or debilitated to walk on the treadmill.  This type of test uses a drug (Dobutamine or Adenosine) which is infused into the bloodstream to increase the heart rate or to affect the flow of blood within the heart and an echocardiogram is used to obtain images of the heart.  This allows physicians to obtain a complete diagnostic reading on how the heart reacts to stress. The pictures obtained before and during stress show how well different parts of the heart are contracting. By comparing how well different areas of the heart contract at baseline and with stress, areas receiving inadequate blood flow due to blockages in the coronary arteries can be identified.

How the test is performed:
A chemical is infused into the bloodstream and then a special camera is used to obtain images of the heart during rest (before the chemical is administered) and  when the heart is in stress (immediately following the chemical being administered). 

 How to prepare for the test:
Patients are generally asked not to eat or drink anything for four to six hours before the test.  Patients scheduled for stress testing may or may not have to continue with their regular medications.  Please follow your physician*s instructions the day of the exam.

How the test will feel:
Electrodes (conductive patches) will be placed on your chest, arms, and legs to record the heart's activity. The preparation of the electrode sites on your chest may produce a mild burning or stinging sensation. The blood pressure cuff on your arm will be inflated every few minutes, producing a squeezing sensation that may feel tight. Baseline measurements of heart rate and blood pressure will be taken before chemical infusion.  The Dobutamine or Adenosine will make the patient feel as though they had walked fast or run up the stairs, including shortness of breath, palpitations, chest pain, and anxiety.